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B Pharm Pharmaceutical Organic Chemistry 3 Pdf Notes


Conquering B. Pharm Pharmaceutical Organic Chemistry 3 can feel like navigating a dense forest of reactions, mechanisms, and complex molecules. But fear not, aspiring pharmacists! Here's your secret weapon: a treasure map to guide you through the undergrowth – powerful B. Pharm Pharmaceutical Organic Chemistry 3 PDF notes!


B Pharm Pharmaceutical Organic Chemistry 3 Notes
B Pharm Pharmaceutical Organic Chemistry 3 Notes

Scope:

This subject imparts knowledge on stereo-chemical aspects of organic compounds and organic reactions, important named reactions, chemistry of important hetero cyclic compounds. It also emphasizes on medicinal and other uses of organic compounds.


Objectives: Upon completion of the subject student shall be able to;

  • Understand the methods of preparation and properties of organic compounds

  • Explain the stereo chemical aspects of organic compounds and stereo chemical reactions

  • know the medicinal uses and other applications of organic compounds


B Pharm Pharmaceutical Organic Chemistry 3 Pdf Notes


Unit 1


Chapter 1 (Stereo isomerism)

Optical isomerism – Optical activity, enantiomerism, diastereoisomerism, meso compounds, Elements of symmetry, chiral and achiral molecules, DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers, Reactions of chiral molecules, Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute.





Unit 2


Chapter 1 (Geometrical Isomerism)

Geometrical isomerism Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems) Methods of determination of configuration of geometrical isomers. Conformational isomerism in Ethane, n-Butane and Cyclohexane. Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity. Stereospecific and stereoselective reactions





Unit 3


Chapter 1 (Heterocyclic compounds)

Nomenclature and classification Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrrole, Furan, and Thiophene Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene





Unit 4


Chapter 1

Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrazole, Imidazole, Oxazole and Thiazole. Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives





Unit 5


Chapter 1 (Reactions of synthetic importance)

Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch reduction, Wolff Kishner reduction. Oppenauer-oxidation and Dakin reaction. Beckmanns rearrangement and Schmidt rearrangement. Claisen-Schmidt condensation


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