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Pharm D 1st Year Organic Chemistry Unit 6 PDF Notes

Updated: Apr 20

Ever wondered how to transform a molecule with a halogen atom and a nearby hydrogen into a molecule with a double bond? Pharm D Organic Chemistry Unit 6 PDF Notes delves into the fascinating world of dehydrohalogenation of alkyl halides, a reaction that eliminates a hydrogen halide and forms a new carbon-carbon double bond. We'll explore the concepts of E1 and E2 mechanisms, two distinct pathways for this reaction, and delve into the evidence that supports each mechanism. We'll also compare and contrast E2 and E1, understand the factors influencing their competition, and explore the fascinating relationship between dehydration of alcohols and dehydrohalogenation. So, pharmacy students, get ready to shed the halogens and embrace the world of double bonds with confidence in Pharm D Organic chemistry PDF Notes!

Pharm D Organic chemistry PDF Notes
Pharm D Organic chemistry PDF Notes

Pharm D Organic Chemistry Unit 6 PDF Notes

Unit 6

Dehydro halogenation of alkyl halides: 1,2 elimination, kinetics, E2 and E1 mechanism, elimination via carbocation, evidence for E2 mechanism, absence of rearrangement isotope effect, absence hydrogen exchange, the element effect, orientation and reactivity, E2 versus E1, elimination versus substitution, dehydration of alcohol, ease of dehydration, acid catalysis, reversibility, orientation.


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